产地国家：意大利
处方药：是
所属类别： 75毫克/胶囊 100胶囊/瓶
包装规格： 75毫克/胶囊 100胶囊/瓶
计价单位：瓶
生产厂家英文名：FARM.RIUNITE SpA
原产地英文商品名：TARGRETIN 75mg/capsules 100capsules/bottle
原产地英文药品名：bexarotene
中文参考商品译名：TARGRETIN软胶囊 75毫克/胶囊 100胶囊/瓶
中文参考药品译名：塔革雷汀
曾用名：贝沙罗汀
简介：
部份中文蓓萨罗丁处方资料（仅供参考）
药品名称：贝沙罗汀
英文名：Bexarotene
商品名：Targretin
药理作用：贝沙罗汀是一种新型的合成维甲酸类似物，它可以选择性地与维甲酸类X受体（RXR）亚单位（RXRa，RXRb，RXRg）结合，因而可以选择性地发挥其功能并可降低临床用药的毒性；它可以抑制造血系统及鳞细胞恶性肿瘤细胞系的生长；它可以诱导一些恶性肿瘤细胞系的程序化死亡；它可以抑制人鳞细胞肿瘤的异种移植物；在鼠皮肤癌模型中它可以明显地抑制乳突淋瘤的生长；对于碳水化合物和脂质代谢研究有应用前景。
制剂的剂型和规格：软胶囊：75毫克/粒；凝胶剂：10g：0.1g(含贝沙罗汀1%)
适应证：用于治疗顽固性皮肤T-细胞淋巴瘤。
用法与用量：软胶囊剂： 300-400毫克/m2/日；凝胶剂用法：1次-4次/日
英文版说明书：
ALTRI ANTINEOPLASTICITARGRETINFL 100CPS 75MGSIGMATAU IND.FARM.RIUNITE SpADescrizione prodottoTARGRETIN*FL 100CPS 75MGPrincipio attivoBEXAROTENEForma farmaceuticaCAPSULEATC livello 3ALTRI ANTINEOPLASTICITipo prodottoFARMACO ETICO————————————————-INDICATIONTargretin® (bexarotene) capsules and gel are used to treat the skin problems arising from a disease called cutaneous T-cell lymphoma， or CTCL， in patients who have not responded well to other treatments. Your healthcare provider must supervise the use of Targretin.IMPORTANT SAFETY INFORMATION INCLUDING PREGNANCY BOXED WARNINGWhat are the most important things I should know about Targretin?Do not take Targretin capsules or use Targretin gel if you are pregnant or if you plan to become pregnantTargretin may harm your fetus (unborn baby). You should contact your healthcare provider immediately if you believe or suspect you are pregnant while being treated with Targretin， and until one month after you stop treatment with Targretin.If you are capable of becoming pregnant， you must have a pregnancy test， within one week before starting Targretin therapy and monthly while you are being treated with Targretin， confirming you are not pregnant.You must use effective contraception (birth control) continuously starting one month before starting treatment with Targretin until one month after you stop treatment with Targretin. It is strongly recommended that two reliable forms of contraception be used together. At least one of these two forms of contraception should include condoms， diaphragms， cervical caps， IUDs， or spermicides.If you are male and your partner is pregnant or capable of becoming pregnant， you should discuss with your healthcare provider the precautions you should take.